Melitta Schachner Selected Research

Cell Adhesion Molecules

1/2020	Cell adhesion molecule close homolog of L1 binds to the dopamine receptor D2 and inhibits the internalization of its short isoform.
9/2019	Glioma malignancy is linked to interdependent and inverse AMOG and L1 adhesion molecule expression.
12/2015	Interaction between CHL1 and serotonin receptor 2c regulates signal transduction and behavior in mice.
3/2013	Neuregulin 1 enhances cell adhesion molecule l1 expression in human glioma cells and promotes their migration as a function of malignancy.
7/2009	O-glycosylation pattern of CD24 from mouse brain.
12/2007	L1 is associated with favorable outcome in neuroblastomas in contrast to adult tumors.
11/2007	L1 is associated with micrometastatic spread and poor outcome in colorectal cancer.
3/2006	Absence of L1 in pancreatic masses distinguishes adenocarcinomas from poorly differentiated neuroendocrine carcinomas.
8/2005	Cell adhesion molecule l1-transfected embryonic stem cells with enhanced survival support regrowth of corticospinal tract axons in mice after spinal cord injury.
9/2003	Soluble cell adhesion molecule L1-Fc promotes locomotor recovery in rats after spinal cord injury.

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Melitta Schachner Research Topics

Disease

49	Spinal Cord Injuries (Spinal Cord Injury) 12/2022 - 02/2003
23	Neoplasms (Cancer) 01/2020 - 01/2006
12	Gliosis 11/2021 - 02/2004
11	Alzheimer Disease (Alzheimer's Disease) 10/2022 - 01/2006
10	Wounds and Injuries (Trauma) 08/2022 - 01/2010
10	Neoplasm Metastasis (Metastasis) 12/2018 - 09/2002
9	Neurodegenerative Diseases (Neurodegenerative Disease) 06/2020 - 01/2006
7	Fasciculation (Fasciculations) 01/2015 - 10/2002
6	Cicatrix (Scar) 11/2021 - 10/2013
6	Nervous System Trauma 01/2019 - 01/2012
6	Parkinson Disease (Parkinson's Disease) 11/2017 - 11/2009
6	Schizophrenia (Dementia Praecox) 11/2015 - 06/2005
5	Glioma (Gliomas) 01/2020 - 03/2013
5	Carcinogenesis 09/2019 - 03/2013
4	Neuroblastoma 06/2020 - 12/2007
4	Mental Disorders (Mental Disorder) 01/2020 - 02/2007
4	Inflammation (Inflammations) 01/2018 - 10/2013
4	Peripheral Nerve Injuries 11/2012 - 11/2007
4	Huntington Disease (Huntington's Disease) 06/2012 - 11/2006
3	Glioblastoma (Glioblastoma Multiforme) 12/2018 - 03/2013
3	Peripheral Nervous System Diseases (PNS Diseases) 01/2018 - 11/2002
3	Nervous System Diseases (Neurological Disorders) 01/2015 - 10/2013
3	Cognitive Dysfunction 08/2011 - 01/2011
2	Infections 08/2022 - 01/2017
2	Ischemia 09/2021 - 06/2016
2	Intellectual Disability (Idiocy) 11/2015 - 12/2002
2	Spinal Cord Compression 03/2014 - 02/2012
2	Neuroinflammatory Diseases 02/2014 - 06/2012
2	Necrosis 06/2012 - 07/2006
2	Multiple Sclerosis 06/2012 - 01/2006
2	Teratoma (Teratoid Tumor) 05/2012 - 06/2006
2	Hirschsprung Disease (Hirschsprung's Disease) 12/2010 - 04/2006
2	Adenocarcinoma 04/2009 - 03/2006
2	Melanoma (Melanoma, Malignant) 04/2007 - 09/2002
1	Autoimmune Diseases (Autoimmune Disease) 08/2022
1	Brain Ischemia (Cerebral Ischemia) 09/2021
1	Demyelinating Diseases (Demyelinating Disease) 01/2021
1	Adducted Thumbs) Syndrome Shuffling Gait Aphasia MASA (Mental Retardation 01/2021

Drug/Important Bio-Agent (IBA)

33	Neural Cell Adhesion Molecule L1 (L1 Cell Adhesion Molecule)IBA 12/2022 - 09/2002
16	Neural Cell Adhesion Molecules (Neural Cell Adhesion Molecule)IBA 01/2016 - 10/2002
14	Proteins (Proteins, Gene)FDA Link 01/2019 - 11/2002
11	Cell Adhesion MoleculesIBA 01/2020 - 09/2002
10	Peptides (Polypeptides)IBA 11/2021 - 03/2003
8	CarbohydratesIBA 07/2021 - 09/2009
7	TenascinIBA 01/2021 - 10/2010
6	Glycoproteins (Glycoprotein)IBA 01/2021 - 02/2004
5	Chondroitin Sulfate ProteoglycansIBA 01/2020 - 01/2012
5	Messenger RNA (mRNA)IBA 02/2014 - 02/2003
5	Monoclonal AntibodiesIBA 04/2012 - 11/2007
4	Amyloid (Amyloid Fibrils)IBA 10/2022 - 01/2013
4	EnzymesIBA 08/2022 - 07/2006
4	Chondroitin Sulfates (Chondroitin Sulfate)IBA 11/2021 - 01/2012
4	tenascin RIBA 04/2009 - 02/2004
3	PerforinIBA 08/2022 - 11/2017
3	Pharmaceutical PreparationsIBA 01/2018 - 11/2006
3	CytokinesIBA 01/2018 - 07/2007
3	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 11/2017 - 11/2009
3	MorpholinosIBA 01/2016 - 09/2004
3	ParaffinIBA 02/2012 - 01/2006
3	polysialic acidIBA 01/2010 - 06/2009
3	Immunoglobulins (Immunoglobulin)IBA 01/2006 - 01/2003
2	Tacrine (Cognex)FDA Link 01/2021 - 01/2018
2	Protein Kinases (Protein Kinase)IBA 01/2020 - 02/2010
2	honokiolIBA 12/2018 - 01/2017
2	Phenelzine (Nardil)FDA Link 01/2018 - 01/2018
2	Polysaccharides (Glycans)IBA 01/2018 - 01/2010
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2018 - 01/2018
2	Interleukin-6 (Interleukin 6)IBA 01/2018 - 01/2018
2	MicroRNAs (MicroRNA)IBA 01/2017 - 05/2011
2	Small Interfering RNA (siRNA)IBA 01/2017 - 03/2013
2	5-nonyloxytryptamineIBA 06/2016 - 01/2014
2	Vinorelbine (Navelbine)FDA LinkGeneric 06/2016 - 01/2016
2	Prion ProteinsIBA 06/2016 - 02/2003
2	ParvalbuminsIBA 11/2015 - 07/2005
2	PTEN Phosphohydrolase (PTEN Phosphatase)IBA 06/2015 - 11/2014
2	TensinsIBA 06/2015 - 11/2014
2	AntibodiesIBA 10/2014 - 04/2007
2	HMGB1 Protein (HMG1)IBA 02/2014 - 06/2012
2	polysialyl neural cell adhesion moleculeIBA 01/2014 - 08/2007
2	Chondroitin ABC LyaseIBA 01/2013 - 07/2012
2	CollagenIBA 11/2012 - 01/2012
2	LectinsIBA 12/2009 - 04/2007
2	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 07/2007 - 03/2003
2	Protein Isoforms (Isoforms)IBA 07/2006 - 02/2003
2	Myelin P0 Protein (Myelin Protein Zero)IBA 05/2004 - 03/2003
1	Membrane Glycoproteins (Membrane Glycoprotein)IBA 12/2022
1	GlycosaminoglycansIBA 11/2021
1	Neuroprotective AgentsIBA 09/2021
1	Duloxetine Hydrochloride (Cymbalta)FDA Link 01/2021
1	Thymidine KinaseIBA 01/2021
1	Cholinergic Agents (Cholinergics)IBA 01/2021
1	Aspartic Acid (Aspartate)FDA Link 01/2021
1	Ganciclovir (Cytovene)FDA LinkGeneric 01/2021
1	Cadherins (E-Cadherin)IBA 01/2020
1	Dopamine Receptors (Dopamine Receptor)IBA 01/2020
1	Myristoylated Alanine-Rich C Kinase SubstrateIBA 01/2020
1	Histone Deacetylase 2IBA 01/2020

Therapy/Procedure

14	Therapeutics 01/2020 - 03/2007
9	Transplantation 04/2016 - 06/2006
2	Isogeneic Transplantation 01/2010 - 06/2006